Progress and prospects: Biological properties and technological advances of herpes simplex virus type 1-based amplicon vectors

Flow cytometric assessment of transducti

Flow cytometric assessment of transduction efficiency and cytotoxicity of herpes simplex virus type 1-based amplicon vectors

✍ Rafael Nunez; Mathias Ackermann; Yoshinaga Saeki; Antonio Chiocca; Cornel Fraefe 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 285 KB

## Background: In this study, we compared herpes simplex virus type 1 (hsv-1) amplicon vector stocks prepared by transient cotransfection with two different bac-cloned packaging-defective hsv-1 helper genomes, fhsvdeltapacdelta27 and fhsvdeltapac, with respect to transduction efficiency and cytotox