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Programmed death-1 (PD-1)-dependent functional impairment of CD4+T cells in recurrent genital papilloma

✍ Scribed by Dong-Yeop Chang, Sang Hoon Song, Sooseong You, Jino Lee, Jihye Kim, Vito Racanelli, Hwancheol Son, Eui-Cheol Shin


Book ID
120963810
Publisher
Springer
Year
2013
Tongue
English
Weight
402 KB
Volume
14
Category
Article
ISSN
0372-8722

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## Abstract Adult T‐cell leukemia/lymphoma (ATL) is a CD4^+^CD25^+^ T‐cell malignancy infected with human T‐cell leukemia virus type‐I (HTLV‐I). HTLV‐I infection causes the T‐cell dysfunction, which contributes to the immunodeficient state of the patients. Programmed death‐1 (PD‐1) can negatively r