## Abstract ## Background Proteins regulating the cell cycle and cell death are frequently abnormally expressed in cancer. Several of these, particularly p53 and Bclβ2, have been widely suggested as possible prognostic markers in diverse human malignancies. Their role in predicting outcome in squa
Prognostic value of the expression of p53 and bcl-2 in patients with laryngeal carcinoma
β Scribed by J. Klatka
- Publisher
- Springer-Verlag
- Year
- 2001
- Tongue
- English
- Weight
- 36 KB
- Volume
- 258
- Category
- Article
- ISSN
- 0302-9530
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Many studies have tried to discriminate malignant from benign phaeochromocytomas, but until now no widely accepted histological, immunohistochemical, or molecular methods have been available. In this study of 29 malignant and 85 benign phaeochromocytomas from 102 patients, immunohistochemistry was p
We investigated immunohistochemically the clinical relevance of the over-expression of the apoptosis-regulating proteins p53 and bcl-2 in a homogeneous series of 149 laryngeal squamous-cell carcinomas. p53 was over-expressed in 75 cases and bcl-2 in 39 cases. p53 and bcl-2 co-expression was found in
BACKGROUND. The clinical course of laryngeal squamous cell carcinoma (LSCC) varies considerably among patients. New biologic markers are needed to facilitate the stratification of individual patients within the conventional clinicopathologic stages of LSCC. METHODS. Eighty-three LSCCs from an equal