Prognostic value of electrodiagnosis in Guillain-Barré syndrome
✍ Scribed by Dr. Robert G. Miller; Dr. Gordon W. Peterson; Dr. Jasper R. Daube; Dr. James W. Albers
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 427 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0148-639X
No coin nor oath required. For personal study only.
✦ Synopsis
This study was designed to identify clinical and electrodiagnostic indicators of prognosis in Guillain-Barr6 syndrome (GBS). Sixty severe GBS patients (all bedfast, 22 ventilator dependent) were analyzed clinically and with standard electromyography and nerve conduction studies. Both ventilator dependence and rapid evolution of weakness were more common in patients with a poor prognosis. The most powerful predictor of a poor outcome was reduced mean compound muscle action potential amplitude (less than 10% of the lower limit of normal).
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Specific treatment has been shown to shorten the duration of mechanical ventilation in Guillain-Barre ´syndrome (GBS) and could obviate the need for tracheostomy in a significant proportion of patients. However, the factors predictive of prolonged ventilation are undetermined, and the timing and use
Guillain-Bar& syndrome (GBS) is a recognizable entity for which the basis for diagnosis is descriptive in our present state of knowledge. Diagnosis rests upon pattern recognition of the clinical picture plus other features including elevated cerebrospinal fluid protein level, electrophysiological ch