Prognostic validity of the familial subtypes of depression

✍ Scribed by Mark Zimmerman; William Coryell; Bruce Pfohl; Dalene Stangl

• Publisher: Springer-Verlag
• Year: 1988
• Tongue: English
• Weight: 449 KB
• Volume: 237
• Category: Article
• ISSN: 1433-8491
• DOI: 10.1007/bf00451285

✦ Synopsis

We examined the prognostic validity of Winokur's familial subtypes of depression in 184 inpatients with primary unipolar major depression Patients with familial pure depressive disease had a more favorable hospital course and reported less symptoms during a 6-month follow-up evaluation than patients with depressive spectrum disease or sporadic depressive disease Consistent with previous studies of the validity of the familial subtypes, the use of stringent thresholds to diagnose the patient's relatives increased the validity of classification.