analysis, the patients were divided into two groups: those with the leukemia type ATL and those with the lymphoma type. The prognostic factors have been evaluated separately for each of the types as well.
Prognostic significance of the proportion of Ki-67-positive cells in adult t-cell leukemia
β Scribed by Yasuaki Yamada; Ken Murata; Sunao Atogami; Kunihiro Tsukasaki; Hisashi Sohda; Takao Yanagisako; Saburo Momita; Toru Jubashi; Tatsuhiko Amagasaki; Kazutaka Kuriyama; Yukinobu Oyakawa; Masuko Tagawa; Michito Ichimaru; Masao Tomonaga; Shimeru Kamihira; Ken-Ichiro Kinoshita
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 481 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0008-543X
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Background. The authors conducted a survey of a large cohort of patients with adult T-cell leukemia (ATL) and a group of human T-cell leukemia virus type 1 (HTLV-1) carriers to elucidate whether measurements of soluble interleukin-2 receptor (sIL-2R) levels are indicative of ATL tumor burden and cor
Adult T-cell leukemia (ATL) is one of the most difficult diseases to treat because of severe underlying immune deficiency and metabolic disturbance. Interferon has potent antiviral, antiproliferative, and immunomodulating properties, and therefore, this may be a good agent to treat such immune defic