Prognostic significance of proliferating cell nuclear antigen expression in hepatocellular carcinoma
โ Scribed by Irene O. L. Ng; Edward C. S. Lai; Sheung T. Fan; Matthew Ng; Annie S. Y. Chan; Mike K. P. So
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 621 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0008-543X
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lmmunostaining for proliferating cell nuclear antigen (PCNA), a marker of cell proliferation, is being increasingly used to study the proliferative activity of tumors, and the PCNA labeling index has been correlated with the prognosis of several malignant neoplasms. Formalin-fixed, paraffin-embedded
## BACKGROUND. Cell proliferative activity is an important indicator of growth and behavior of various human tumors. Immunostaining of tissue sections with proliferating cell nuclear antigen (PCNA) and Ki-67 antibodies appears to be reliable in the assessment of tumor cell proliferation. This study