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Prognostic Significance of p53 andrasGene Abnormalities in Lung Adenocarcinoma Patients with Stage I Disease after Curative Resection

✍ Scribed by Isobe, Takeshi ;Hiyama, Keiko ;Yoshida, Yasuhiro ;Fujiwara, Yasuhiro ;Yamakido, Michio

Book ID
108580931
Publisher
Wiley (Blackwell Publishing)
Year
1994
Tongue
English
Weight
479 KB
Volume
85
Category
Article
ISSN
0910-5050

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p53 tumour suppressor gene alterations are one of the most frequent genetic events in lung cancer. A subset of patients with p53 mutation and cancer exhibited circulating serum anti-p53 self-antibodies (p53-Ab). The prevalence of these antibodies in lung cancer is currently being analysed in a multi