Prognostic significance of p16INK4a immunocytochemistry in adult ALL with standard risk karyotype
โ Scribed by Soenen, V; Lepelley, P; Gyan, E; Preudhomme, C; Lai, J-L; Bauters, F; Fenaux, P; Quesnel, B
- Book ID
- 110054919
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 179 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0887-6924
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The __p16__^INK4a^ gene, localized within chromosome 9p21, has been identified as a cyclinโdependent kinase inhibitor and may negatively regulate the cell cycle acting as a tumor suppressor. Genetic alterations involving the 9p21 region are common in human cancers. A consecutive series
## Abstract Even though p16^INK4a^ (p16) immunocytochemistry has proven a useful accessory tool verifying the identification of atypical squamous cells of undetermined significance (ASCโUS) categorized smears, the procedure still has limitations. To date few studies examining the usefulness of p16