Prognostic significance of nuclear DNA content in small cell carcinoma of the lung
β Scribed by Shosaku Abe; Shiro Makimura; Koichi Itabashi; Tatsuo Nagai; Yasuhiro Tsuneta; Yoshikazu Kawakami
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 451 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0008-543X
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π SIMILAR VOLUMES
## BACKGROUND. A multiple sampling study was performed on 124 specimens of renal cell carcinomas to analyze the consistency and reliability of DNA measurements. The authors investigated intratumoral DNA heterogeneity and its role as a adverse prognostic factor for disease progression. ## METHODS
Two hundred-twelve consecutive patients with small cell carcinoma of the lung were studied in order to correlate the risk of developing intracranial metastases to the initial stage of the disease (locoregional versus extensive) and to evaluate the prognostic significance of developing intracranial d