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Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas

✍ Scribed by Yosuke Hashimoto; Marek Skacel; Ian C Lavery; Abir L Mukherjee; Graham Casey; Josephine C Adams


Book ID
119897186
Publisher
BioMed Central
Year
2011
Tongue
English
Weight
67 KB
Volume
11
Category
Article
ISSN
1471-2407

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## BACKGROUND. The Ocl-2 oncoprotein confers a survival advantage to cells by inhibiting programmed cell death (PCD) or apoptosis. Overexpression of bcl-2 probably plays a role in colorectal carcinogenesis. The aims of our study were to determine bcl-2 expression and PCD index in colorectal adenom