Prognostic significance of estrogen receptor alpha and beta expression in human serous carcinomas of the ovary
✍ Scribed by Alexander Burges; Ansgar Brüning; Christine Dannenmann; Thomas Blankenstein; Udo Jeschke; Naim Shabani; Klaus Friese; Ioannis Mylonas
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 469 KB
- Volume
- 281
- Category
- Article
- ISSN
- 0003-9128
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Estrogens have an important function in the natural history of uterine leiomyomata. The human estrogen receptor beta gene (ESR2) has been identified recently and mapped to 14q22-24, a region frequently rearranged in uterine leiomyomata and other benign tumors, including pulmonary chondroid hamartoma
Estrogen receptor alpha (ER␣) and estrogen receptor beta (ER) mRNAs are both expressed in rat dorsal root ganglion (DRG) neurons, but the distribution of these two mRNAs differs markedly. Radiolabeled probes highly specific to ER␣ or ER mRNAs were used for in situ hybridization studies; two antibo