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Prognostic Significance of E-cadherin Expression and Peripheral Blood Micrometastasis in Gastric Carcinoma Patients

✍ Scribed by Abeer A. Saad; Nahla M. Awed; Nashwa N. A. Abd Elkerim; Dina EL-Shennawy; Marian A. Alfons; Mohamed E. Elserafy; Yaser W. Darwish; Eman M. F. Barakat; Sahar S. Ezz-Elarab

Book ID
111773665
Publisher
Springer
Year
2010
Tongue
English
Weight
474 KB
Volume
17
Category
Article
ISSN
1068-9265

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E-cadherin is a Ca2+-dependent intercellular adhesion molecule known to exert an invasion-suppressor function. In the present study, E-cadherin expression was imrnunohistochemically investigated in a retrospective series of 4 I 3 RO-resected gastric carcinomas using the monoclonal antibody (MAb) 5H9

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## BACKGROUND. Thomsen-Freidenreich (T) antigen, the immediate precursor antigen of the human blood MN system, has been detected in malignant cells, but not in most normal cells in which it is cryptic but can be unmasked by desialylation. In this study, we determined the prognostic significance of