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Prognostic role of global DNA-methylation and histone acetylation in pT1a clear cell renal carcinoma in partial nephrectomy specimens

✍ Scribed by D. Minardi; G. Lucarini; A. Filosa; G. Milanese; A. Zizzi; R. Di Primio; R. Montironi; G. Muzzonigro


Book ID
114778513
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2008
Tongue
English
Weight
772 KB
Volume
13
Category
Article
ISSN
1582-1838

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## Abstract Epigenetic alterations play an important role in carcinogenesis. Recent studies suggested that global histone modifications are predictors of cancer recurrence in various tumor entities. Our study was performed to evaluate histone H3 lysine 4 mono‐methyl (H3K4me1), ‐di‐methyl (H3K4me2)