Prognostic markers for survival in patients with metastatic renal cell carcinoma treated with interleukin-2
✍ Scribed by Rutger L. van Bezooijen; H. Goey; Gerrit Stoter; J. Hermans; G. J. Fleuren
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 473 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0340-7004
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## Abstract We investigated the biological response of 73 patients with metastatic renal‐cell carcinoma (MRCC) treated by repetitive weekly cycles of high‐dose interleukin 2 (IL‐2) (protocol 1, 40 patients) or IL‐2 plus interferon‐gamma (IFN‐γ) (protocol 2, 33 patients). The objectives of this stud
## Abstract ## BACKGROUND. In a randomized, phase 3 trial, sunitinib demonstrated superior efficacy over interferon‐alfa as first‐line therapy in patients with metastatic clear‐cell renal cell carcinoma (RCC). On the basis of outcome data from that trial, the authors developed a nomogram for predi
The authors thank S. Ne ´grier, M.D., A. Ravaud, M.D., and G. Chvetzoff for providing the clinical charts of patients included in the external data set.