Prognostic influence of p53 nuclear overexpression in colorectal carcinoma
✍ Scribed by M. Galindo Gallego; M. J. Fernández Aceñero; J. Sanz Ortega; A. Aljama Delgado; J. L. Balibrea Cantero
- Book ID
- 105507029
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 615 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0012-3706
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
The prognosis of operated patients with non-small cell lung cancer (NSCLC) is poor despite thorough pre-operative staging. An improved preselection is needed of patients likely to profit from surgery. This study was undertaken to evaluate the prognostic significance of nuclear p53 overexpression in
The products of bcl-2 and p53 genes are involved in the regulation of apoptosis and proliferation and have been associated with prognosis in several malignancies, including colorectal adenocarcinoma. Although 2 European studies have reported a prognostic significance of Bcl-2 expression in colorecta
Background and Objectives: Precise evaluation of the prognostic factors for hematogenic recurrence after resection for colorectal cancer is important not only for the prediction of patient outcome but also for the determination of adjuvant therapy. The purpose of the current study was to elucidate t
## Abstract ## Background The role of p53 expression in human neoplasms is still controversial, and it has been associated with both favorable and unfavorable outcome of the patients. Also cytoplasmic expression of p53 protein has been reported to affect survival in some cancers. Furthermore, an a
## Abstract The influence of __p53__ mutations on the response to ionizing radiation and survival was retrospectively evaluated in patients treated with preoperative radiotherapy for rectal carcinoma. From 1989 to 1991, 86 rectal cancer patients treated by preoperative radiotherapy were included in