## Background: Disease stage at the time of diagnosis and response to therapy are the main prognostic factors for patients with ewing sarcoma or peripheral neuroectodermal tumor (es/pnet). the primary genetic alteration in es/pnet, the fusion of the ews gene with fli1 or erg, is diagnostically high
Prognostic impact of INK4A deletion in Ewing sarcoma
β Scribed by Guo Wei; Cristina R. Antonescu; Enrique de Alava; Denis Leung; Andrew G. Huvos; Paul A. Meyers; John H. Healey; Marc Ladanyi
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 112 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0008-543X
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Ewing's sarcoma, peripheral primitive neuroectodermal tumors, and Askin tumors are referred to as Ewing tumors (ETs), and are characterized by high MIC2 expression and a t(11;22)(q24;q12) or other rearrangements involving 22q12. In addition to these constant aberrations, facultative numerical and st
## Background: The cooperative ewing sarcoma study (cess 86), conducted by the german society of pediatric oncology and hematology (gpoh), was planned on the basis of the results of the preceding cess 81 study. the prognostic significance of tumor volume in localized ewing sarcoma of bone was well
High-dose methotrexate (HDMTX), adriamy-overall and disease-free survival rates were 70% cin (ADR), and cisplatinum (CDDP) are effective and 59%, respectively. Factors which favorably agents in the treatment of osteogenic sarcoma influenced prognosis on univariate analysis were (OS). Individual pati