Prognostic features, human papillomavirus status, and epidermal growth factor receptor expression in oral squamous cell carcinoma in young adults
โ Scribed by Ligy Thomas; Eric J. Moore; Michaela E. McGree; Kerry D. Olsen; Jan L. Kasperbauer; Lori A. Erickson; David J. Schembri-Wismayer
- Book ID
- 119187844
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 297 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1532-818X
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To evaluate the clinical significance of the expression of epidermal growth factor receptor (EGFr) in oral squamous cell carcinoma (SCC), 100 formalin-fixed, paraffin-embedded cases of this tumour and ten samples of normal oral mucosa were immunostained with a monoclonal anti-EGFr antibody using an
## Abstract ## Background. The epidermal growth factor receptor (EGFR) and the inhibitor of apoptosis protein survivin play important roles in the regulation of cellular proliferation and survival in squamous cell carcinomas. Their correlation in oropharyngeal squamous cell carcinoma (OSCC) has no