𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Prognostic factors in superficial adult soft tissue sarcomas: Analysis of a series of 105 patients

✍ Scribed by Cany, Laurent; Stoeckle, Eberhard; Coindre, Jean-Michel; Kantor, Guy; Bonichon, Fran�oise; Bui, Binh Nguyen


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
101 KB
Volume
71
Category
Article
ISSN
0022-4790

No coin nor oath required. For personal study only.

✦ Synopsis


Background and objectives:

This study was undertaken to study the behavior of superficial soft tissue sarcomas (sts) and determine the factors related to prognosis.

Methods:

The clinical records of 105 adults (56 men, 49 women, mean age: 56.4 years) were retrospectively analyzed. univariate analysis was performed on the entire group for overall survival (os), and metastasis-free survival (mfs). local recurrence-free survival (lrfs) was studied only on patients first treated in our institute.

Results:

With a median follow-up of 111.9 months, 66 (62.9%) patients were alive; 25 (23.8%) had died of their disease. for the entire series, 10-year os and mfs were 62.5% and 71.9% respectively. for fifty-two patients treated for their sarcoma at the institution since the first tumor occurrence event, 10-year lrfs was 80%. tumor grade was the only factor correlated with os and mfs, while tumor size was the main factor correlated with lrfs.

Conclusion:

Tumor size affects local control in sts while tumor grade is correlated with os and mfs.


📜 SIMILAR VOLUMES


Analysis of clinicopathologic prognostic
✍ Patricia Pautier; Catherine Genestie; Annie Rey; Philippe Morice; Béatrice Roche 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB 👁 1 views

BACKGROUND. Uterine sarcomas (US) are rare and carry a poor prognosis characterized by high rates of local recurrence and metastasis. The aim of this study was to test, for what the authors believe was the first time with US, the prognostic impact of the histologic grade validated by the French Fede

Predictive factors for complete removal
✍ Sastre-Garau, Xavier; Coindre, Jean-Michel; Leroyer, Ariane; Terrier, Philippe; 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 359 KB 👁 1 views

## Background and Objectives: In order to specify the indications for conservative surgery and preoperative therapeutic approaches of soft tissues sarcomas (STS), we looked for the clinico-pathological parameters associated with the failure to obtain a complete removal (CRm) of the tumor. Methods:

Prognostic factors in retroperitoneal sa
✍ Eberhard Stoeckle; Jean-Michel Coindre; Sylvie Bonvalot; Guy Kantor; Philippe Te 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 131 KB 👁 2 views

## BACKGROUND. Surgery is the main prognostic factor in retroperitoneal sarcoma. However, despite progress, surgery alone is rarely curative, and analysis of the causes of failures and of other prognostic factors are warranted to ascertain treatment orientations.

Flow cytometric DNA content analysis of
✍ Françoise Collin; Agnès Chassevent; Françoise Bonichon; Gérard Bertrand; Philipp 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 120 KB 👁 1 views

## Background: The authors determined the flow cytometric (fcm) dna characteristics of 53 benign tumors and 132 malignant (71 primary, 61 recurrent) soft tissue sarcomas to investigate their heterogeneity and to evaluate the prognostic values of dna ploidy status and s-phase fraction (spf). ## Met