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Prognostic factors in patients with minor salivary gland carcinoma of the oral cavity and oropharynx

✍ Scribed by José F. Carrillo; Federico Maldonado; Liliana C. Carrillo; Margarita C Ramirez-Ortega; Juan G. Gómez Pizano; C. Melo; José G Chanona; K. Luna-Ortiz; Luis F. Oñate Ocaña

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
401 KB
Volume
33
Category
Article
ISSN
1043-3074

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✦ Synopsis

Background. This study was performed to define prognostic factors and management of minor salivary gland carcinoma of the oral cavity and oropharynx .

Methods. Retrospective analyses of patients with salivary gland carcinoma of the oral cavity or oropharynx, treated in 1989 to 2006. Statistics included univariate analyses to identify prognostic factors associated with disease-free survival (DFS) and disease-specific survival. A multivariate analysis model was constructed by the Cox method.

Results. Seventy-seven patients constituted our cohort. Significant prognostic factors regarding DFS and disease-specific survival in univariate analyses comprised tumor size, surgical margins, grade, lymph node status, and Karnofsky status and T classification. A multivariate model identified tumor size, grade, surgical margins, and lymph node status significant regarding DFS.

Conclusions. Tumor size, grade, surgical margins, and lymph node status could be used for a rational design of treatment strategies in these rare tumors. V

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