Prognostic factors in papillary carcinoma of the thyroid

✍ Scribed by Anne-Marie Schindler; Guy van Melle; Beatrice Evequoz; Bianca Scazziga

• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 683 KB
• Volume: 68
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(19910715)68:2<324::aid-cncr2820680220>3.0.co;2-s

✦ Synopsis

In a retrospective study of 119 patients, followed for 1 to 30 years after treatment of a papillary carcinoma of the thyroid, the authors searched for possible prognostic factors of the risk of recurrence. Microcarcinomas, anaplastic tumors and Hürthle cell carcinomas were excluded from the study. In a univariate analysis, age (greater than 45 years), sex (male), loss of histologic differentiation, size (greater than 3 cm), presence of carcinomatous lymphangitis, extrathyroid extension, and presence of metastasis at diagnosis were associated with a higher recurrence rate; type of growth and multifocality were not significant. In a multivariate analysis (logistic regression), age, size, and carcinomatous lymphangitis were significant predictors for women, whereas metastasis at diagnosis and cystic growth were significant for men.