Prognostic Factors in Papillary and Follicular Thyroid Carcinomas : p53 Expression Is a Significant Indicator of Prognosis
✍ Scribed by Christian Godballe; Pia Asschenfeldt; Karsten E. Jørgensen; Lars Bastholt; Per P. Clausen; Tine P. Hansen; Olfred Hansen; Søren M. Bentzen
- Book ID
- 110079578
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 675 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0023-852X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## BACKGROUND. Numerous clinical parameters have been suggested as predictors of outcome for patients with head and neck carcinoma treated with radiation therapy, but their applicability remains controversial. Inactivation of the p53 tumor suppressor results in radioresistance in experimental syst
The purpose of our study was to determine the expression of the pro-apoptotic BAX protein in relation to the mutational status of BAX and p53 (as transcriptional activator of the BAX gene) in benign and malignant thyroid tissue. In 47 patients with thyroid tumours (14 follicular and 3 papillary carc
## Abstract Deregulation of cell death pathways contributes to tumor development and to the clinical course of cancer disease. In patients with liver metastases of colorectal cancer, we have previously shown that an intact p53/BAX apoptotic pathway is a positive prognostic factor. Therefore, the pu