## Abstract ## BACKGROUND After randomized trials in the 1980s, doxorubicin (DOX) was added to dactinomycin plus vincristine as standard chemotherapy for patients who had Stage III Wilms tumor (WT) of favorable histology (FH). Doubleβagent chemotherapy was retained for patients with Stage II disea
Prognostic factors in nonmetastatic, favorable histology wilms' tumor. Results of the third national wilms' tumor study
β Scribed by Norman Breslow; Katrina Sharples; J. Bruce Beckwith; Janice Takashima; Panayotis P. Kelalis; Daniel M. Green; Giulio J. D'Angio
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 802 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0008-543X
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The purpose of this study was to evaluate the effect of the sequential addition of doxorubicin and cyclophosphamide to the combination of vincristine and actinomycin D o n the relapse-free survival of children with stage IV/favorable histology Wilms tumor. We reviewed the clinical courses of all ran
## BACKGROUND. Approximately 1% of children with unilateral Wilms tumor develop contralateral disease. The authors assessed the demographic and histologic features associated with metachronous bilateral Wilms tumor (BWT). ## METHODS. Characteristics of all children registered on the first four Nat