## Abstract Assessment of __HER2/neu__ oncogene has been used as both a prognostic and predictive marker for breast cancer. However, the choice of the best method to assess the status of __HER2/neu__ oncogene in breast cancer tissue remains controversial. A variety of techniques are available to de
โฆ LIBER โฆ
Prognostic and predictive implications of HER2/ERBB2/neu gene mutations in lung cancers
โ Scribed by Tomizawa, Kenji; Suda, Kenichi; Onozato, Ryoichi; Kosaka, Takayuki; Endoh, Hideki; Sekido, Yoshitaka; Shigematsu, Hisayuki; Kuwano, Hiroyuki; Yatabe, Yasushi; Mitsudomi, Tetsuya
- Book ID
- 119320543
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 632 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0169-5002
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## Abstract __Vโerbโb2__ erythroblastic leukemia viral oncogene homolog 2 (__ERBB2;__ synonyms __HER2, NEU__) encodes a transmembrane glycoprotein with tyrosine kinaseโspecific activity that acts as a major switch in different signalโtransduction processes. __ERBB2__ amplification and overexpressio