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Progesterone receptor downregulates breast cancer resistance protein expression via binding to the progesterone response element in breast cancer

✍ Scribed by Xiaojuan Wu; Xiaofang Zhang; Hui Zhang; Peng Su; Weiwei Li; Li Li; Yan Wang; Wenjun Liu; Peng Gao; Gengyin Zhou


Book ID
114703220
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
779 KB
Volume
103
Category
Article
ISSN
1347-9032

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This review presents our experience with the use of estrogen receptors (ER) and progesterone receptors (PgR) in the prediction of response to endocrine therapy in stage IV breast cancer. Presence of ER (>3 fmoUmg cytosol protein) significantly predicted response to the antiestrogen tamoxifen and to