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Progesterone-induced DNA polymerase activity in full-grown oocytes of xenopus laevis

✍ Scribed by Grippo, P. ;Locorotondo, G. ;Taddei, C.


Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
309 KB
Volume
200
Category
Article
ISSN
0022-104X

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✦ Synopsis


Abstract

DNA polymerase activity increases in full‐grown oocytes of Xenopus laevis during in vitro progesterone‐induced maturation. This increase in inhibited by cycloheximide. The presence of the oocyte's nucleus (germinal vesicle) seems essential for the induction of this increase: in previously enucleated oocytes, the level of DNA polymerase activity does not change during progesterone treatment.

Furthermore, a new form of DNA polymerase is detectable by DEAE chromatography in in vitro matured oocytes.