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Progesterone and regulation of the follicle-stimulating hormone (FSH-β) gene

✍ Scribed by James L O’Conner; Marlene F Wade; Dean P Edwards; Virendra B Mahesh

Book ID: 117214116
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 493 KB
Volume: 64
Category: Article
ISSN: 0039-128X
DOI: 10.1016/s0039-128x(99)00038-0

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17 beta-Estradiol (E2) rapidly and reversibly decreases the synthesis of follicle-stimulating hormone (FSH) in primary dispersed cell cultures of ovine pituitaries. Similarly, E2 also causes a decrease in the messenger RNA for the beta subunit of ovine FSH (FSH beta-mRNA) as measured in an in vitro