𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Progenitor cell populations in the periodontal ligament of mice

✍ Scribed by McCulloch, C. A. G.

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
502 KB
Volume
211
Category
Article
ISSN
0003-276X

No coin nor oath required. For personal study only.

✦ Synopsis

Stem cells in a variety of renewal tissues exhibit a slow rate of cell proliferation (Potten et al., 1979). The periodontal ligament of mouse molars was examined for the presence of slowly cycling progenitor cells to provide evidence for the existence of stem cells in this tissue. A pulse injection of 3H-thymidine was administered and mice were sacrificed between 1 hour and 14 days after injection. Analysis of radioautographs using percentage of labeled cells and grain counts demonstrated that a population of label-retaining cells within 10 pm of blood vessels traversed the cell cycle more slowly than proliferating cells located greater than 10 pm from blood vessels. These data suggest that there is a slowly dividing population of progenitor cells in paravascular sites in mouse molar periodontal ligament which may be stem cells.

~~

πŸ“œ SIMILAR VOLUMES

Location of progenitor cells in periodon
Location of progenitor cells in periodontal ligament of mouse molar stimulated by wounding
✍ Gould, T. R. L. ;Melcher, A. H. ;Brunette, D. M. πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 English βš– 751 KB

## Abstract Wounds were made in the alveolar process overlying the mesial root of the mandibular first molar of 35‐g mice to expose periodontal ligament. Dividing cells were arrested in metaphase by injection of vinblastine sulphate three hours before death three, five and seven days after wounding

Investigating a clonal human periodontal
Investigating a clonal human periodontal ligament progenitor/stem cell line in vitro and in vivo
✍ Shinsuke Fujii; Hidefumi Maeda; Naohisa Wada; Atsushi Tomokiyo; Masahiro Saito; πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 406 KB

## Abstract The lifespan of the tooth is influenced by the periodontal ligament (PDL), a specialized connective tissue that connects the cementum with the tooth socket bone. Generation of a cell line from PDL progenitor/stem cells would allow development of tissue engineering‐based regenerative PDL

Histochemical studies of glycosaminoglyc
Histochemical studies of glycosaminoglycans in developing periodontal ligaments of ICR mice
✍ Fujii, Toshihisa ;Hirabayashi, Yoshifumi πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 843 KB

Although the periodontal ligament (PL) contains an abundance of glycosaminoglycans (GAGs), there are only a few histochemical studies describing GAGs in the developing PL. In the present study, the relationship between the formation of principal fibers and the molecular species of GAGs in the develo