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Profiling indomethacin impurities using high-performance liquid chromatography and nuclear magnetic resonance

✍ Scribed by Sonja Hess; Uwe Teubert; Jutta Ortwein; Kurt Eger


Book ID
114301948
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
252 KB
Volume
14
Category
Article
ISSN
0928-0987

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## Abstract The usefulness of applying an integrated LC‐NMR and LC‐MS approach to acarbose bulk drug impurity profiling is demonstrated. LC‐MS and LC‐NMR methodologies were employed for the online separation and structural elucidation of a final drug product. Combining data provided by the stop‐flo