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Profilin 1 overexpression in renal cell carcinoma

✍ Scribed by Satoru Minamida; Masatsugu Iwamura; Yoshio Kodera; Yusuke Kawashima; Masaomi Ikeda; Hiroshi Okusa; Tetsuo Fujita; Tadakazu Maeda; Shiro Baba

Book ID
108980279
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
974 KB
Volume
18
Category
Article
ISSN
0919-8172

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## Abstract Profilin‐1 (Pfn1), a ubiquitously expressed actin‐binding protein, has been regarded as a tumor‐suppressor molecule for breast cancer. Since AKT signaling impacts cell survival and proliferation, in this study we investigated whether AKT activation in breast cancer cells is sensitive to