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Profile of drug metabolizing enzymes in human ileum and colon

✍ Scribed by G.M. Pacificl; M. Franchi; P.G. Gervasi; V. Longo; P. diSimplicio; A. Temellini; L. Giuliani

Book ID
114075701
Publisher
Elsevier Science
Year
1988
Weight
107 KB
Volume
20
Category
Article
ISSN
0031-6989

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## Abstract Sulindac is a nonsteroidal antiinflammatory drug that has been demonstrated to be a potent chemopreventive agent against colorectal cancer in both human and animal models. __In vivo__, sulindac may be reversibly reduced to the active antiinflammatory compound, sulindac sulfide, or irrev