Production of taxanes by Taxus baccata plant cells
✍ Scribed by Tomáš Vaněk; Daniela Veselá; Jana Malá; Radka Podlipná; David Šaman; Jitka Kohoutová
- Publisher
- Springer Netherlands
- Year
- 1996
- Tongue
- English
- Weight
- 259 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0141-5492
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✦ Synopsis
In callus cultures of Tutus baccata grown on agar media according to Murashige and Skoog supplemented with different growth hormones 8 taxol analogues were identified.
📜 SIMILAR VOLUMES
To achieve a better understanding of taxol metabolism and accumulation in Taxus cell cultures, a T. baccata cell line growing for 20 days in a selected growth medium was treated at the beginning of the experiment with several concentrations of taxol (25, 50, 100 and 200mgL(-1)). Compared with an unt
Analytical determination by HPLC of five taxanes-paclitaxel, cephalomannine, 10-deacetylpaclitaxel, 10deacetylcephalomannine and taxcultine-in extracts from the bark of Taxus baccata indicates that taxane concentrations vary seasonally. The highest concentration was found in October and the lowest i