Role of the I-domain in collagen binding
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Andreas Kern; Eugene E. Marcantonio
📂
Article
📅
1998
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John Wiley and Sons
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English
⚖ 172 KB
👁 2 views
Adhesion to collagens by most cell types is mediated by the integrins a1b1 and a2b1. Both integrin a subunits belong to a group which is characterized by the presence of an I domain in the N-terminal half of the molecule, and this domain has been implicated in the ligand recognition. Since purified