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Production of Retroviral Vectors for Gene Therapy with the Human Packaging Cell Line FLYRD18

✍ Scribed by Patrick A. Gerin; Peter F. Searle; Mohamed Al-Rubeai


Book ID
109388273
Publisher
American Institute of Chemical Engineers
Year
1999
Tongue
English
Weight
99 KB
Volume
15
Category
Article
ISSN
8756-7938

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## Abstract The production of gene therapy retroviral vectors presents many difficulties, mainly due to vector instability and low cell productivities hampering the attainment of high titers of infectious viral vectors. The objective of this work is to increase the production titers of retroviral v