Production of recombinant human growth hormone in Escherichia coli: Expression of different precursors and physiological effects of glucose, acetate, and salts
β Scribed by E. Bech Jensen; S. Carlsen
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 813 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0006-3592
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Two Escherichia coli strains, widely used for the production of various recombinant proteins, were compared for their pre-induction growth and acetate accumulation patterns. The strains studied were β¬, coliBL21 (ADES), transformed with a plasmid encoding Pseudomonas exotoxin A, and an β¬. coli K12 de
## Abstract Growth hormone (GH), given therapeutically in many human diseases, is able to modulate the maturation and function of many cells of immune system. The present study demonstrates the effect of human recombinant GH on the production of acute phase proteins (APP) as well as on the gene exp