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Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica

✍ Scribed by Xue, Zhixiong; Sharpe, Pamela L; Hong, Seung-Pyo; Yadav, Narendra S; Xie, Dongming; Short, David R; Damude, Howard G; Rupert, Ross A; Seip, John E; Wang, Jamie; Pollak, Dana W; Bostick, Michael W; Bosak, Melissa D; Macool, Daniel J; Hollerbach, Dieter H; Zhang, Hongxiang; Arcilla, Dennis M; Bledsoe, Sidney A; Croker, Kevin; McCord, Elizabeth F; Tyreus, Bjorn D; Jackson, Ethel N; Zhu, Quinn

Book ID
120608678
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
1021 KB
Volume
31
Category
Article
ISSN
1087-0156

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Due to various special physiological features and a genome that greatly differs in structure, gene content and organization from other yeasts, Y. lipolytica is widely used as a host system. With its characteristics, such as the ability to grow on lipids or grease, to accumulate oil and the high capa