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Production of migration inhibitory factor and lympl toxin by non-T cells

✍ Scribed by B. R. Bloom; G. Stoner; Judith Gaffney; E. Shevach; I. Green

Publisher
John Wiley and Sons
Year
1975
Tongue
English
Weight
321 KB
Volume
5
Category
Article
ISSN
0014-2980

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✦ Synopsis

Abstract

Treatment of tuberculin‐sensitive guinea pig spleen or lymph node cells with a burro anti‐T cell serum plus complement diminished markedly number of functionally detectable T cells, but did not affect the amount of migration inhibitory factor (MIF) or lymphotoxin produced by the residual T cell‐depleted populations.

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## Abstract Attempts were made to reveal the mechanism of the inhibitory effect of lentinan on methylcholanthrene‐in‐duced transplantable fibrosarcoma (A/Ph.MC.SI) isografts. Since the involvement of a delayed‐type hypersensitivity response can be supposed to operate against this syngeneic tumor, t