Production of Hyaluronate and Collagen by Fibroblast Clones in Culture
β Scribed by GREEN, HOWARD; HAMERMAN, DAVID
- Book ID
- 109634225
- Publisher
- Nature Publishing Group
- Year
- 1964
- Tongue
- English
- Weight
- 144 KB
- Volume
- 201
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/201710a0
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Human fibroblasts cultured for 10 days in a collagen sponge migrated through the pores of the sponge and expressed a moderate mitotic activity, which stabilized after 10 days, and a high collagen and protein synthesis. Between 10 and 27 days, the newly synthesized collagen filled the pores of the sp