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Production of HLA antibody in mice immunised with syngeneic mouse–human hybrid cells containing human chromosome 6

✍ Scribed by ADEN, DAVID P.; MAUSNER, RACHEL; KNOWLES, BARBARA B.


Book ID
109708394
Publisher
Nature Publishing Group
Year
1978
Tongue
English
Weight
423 KB
Volume
271
Category
Article
ISSN
0028-0836

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## Abstract Mouse‐human somatic cell hy brids containing human chromosome 17 carrying the region p21→pter of human chromosome 6 and no other human chromosomes, were found to express HLA‐A but not HLA‐B. Counterselection of the hybrid cells in medium containing 5‐bromodeoxyuridine resulted in the gr