A (1 + 3)\_/3-Linked poly-D-glucose immune stimulant is isolated from the inner cell wall of Succ~aromyc~ cerevhiae [1,21 and belongs to the class of drugs known as biological response modifiers (BRMs). This polysaccharide exerts a beneficial effect on a variety of experimentally induced disease sta
Production of extracellular water insoluble β-1,3-glucan (curdlan) fromBacillussp. SNC07
✍ Scribed by Sathyanarayana N. Gummadi; Kislay Kumar
- Publisher
- The Korean Society for Biotechnology and Bioengineering
- Year
- 2005
- Tongue
- English
- Weight
- 244 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1226-8372
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We have extensively investigated (1 + 3)-/3-D-glucan immune stimulants that are isolated from the inner cell wall of Saccharomyces cereuisiue'-4. Natural product (1 + 3)-p-D-glucan homopolysaccharides, which stimulate immunity, belong to the \* Corresponding author.
Extensive surveys for the effects of various P-o&cans on the coagulation cascade in horseshoe crab amebocyte lysates showed that low-mol-wt-(1 + 3)-p-o-glucans and laminaran oligosaccharides inhibit the activation of a limulus coagulation factor G by high-mol-wt-(1 + 3)+?-o-glucans. The inhibitory p