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Production of biologically active IgG hinge-tag soluble epidermal growth factor receptors (ErbB)

✍ Scribed by Takayuki Otani; Toshihiro Hashizume; Tadahiro Nagaoka; Tomoko Fukuda; Careen K. Tang; David S. Salomon; Masaharu Seno

Publisher
Springer Netherlands
Year
2009
Tongue
English
Weight
213 KB
Volume
32
Category
Article
ISSN
0141-5492

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Transforming growth factor-␣ (TGF-␣) and epidermal growth factor (EGF) are members of the EGF family of growth factors. They have a common receptor, the EGF receptor. This belongs to the tyrosine kinase group of receptors called the ErbB receptor family. Other members are ErbB-2, ErbB-3, and ErbB-4.