𝔖 Bobbio Scriptorium
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Production of bi-specific monoclonal antibodies in a hollow-fibre bioreactor

✍ Scribed by A. Gorter; R.J. van de Griend; J.D.H. van Eendenburg; W.H.B. Haasnoot; G.J. Fleuren


Book ID
118902725
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
474 KB
Volume
161
Category
Article
ISSN
0022-1759

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The selection of medium feed rates for perfusion bioreactors represents a challenge for process optimization, particularly in bioreactors that are sampled infrequently. When the present and immediate future of a bioprocess can be adequately described, predictive control can minimize deviations from