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Production of arachidonic acid metabolites by the colon adenocarcinoma cell line HT29 cl.19A and their effect on chloride secretion

โœ Scribed by Serge Battu; Gilles Clement; Martine Heyman; Jean M Wal; Jeanne Cook-Moreau; Jehan F Desjeux; Jean L Beneytout


Book ID
117468502
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
212 KB
Volume
116
Category
Article
ISSN
0304-3835

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The human colonic carcinoma cell line HT-29cl.19A responds to the protein kinase C activator PDB (4-beta-phorbol 12,13-dibutyrate), as it does to forskolin (an activator of adenylyl cyclase), with a secretory response when the cells are grown on filters and studied at 36 degrees C. Previously, we sh