Production of an indolizidine alkaloid, swainsonine by the filamentous fungus,Metarhizium anisopliae

✍ Scribed by M. Patrick; M. W. Adlard; T. Keshavarz

• Book ID: 104633777
• Publisher: Springer Netherlands
• Year: 1993
• Tongue: English
• Weight: 265 KB
• Volume: 15
• Category: Article
• ISSN: 0141-5492
• DOI: 10.1007/bf00129924

✦ Synopsis

The physiology ofMetarhi~um anisophae has been studied with a view to improving swainsonine producUon. In prelimina.~" work, the stability of pure s~ainsonine in aqueous solution has been investigated under varying conditions of pH and temperature and in the presence of oxidizing agents. The effects of o.~.gen on the growth and morpholoKv of M.anisopliae and the production of swainsomne were also examined Shaken flask fermentations have been carried out in order to develop a medium suitable for production of swainsonine.