Production of a valerian galenical using liquefied carbon dioxide
✍ Scribed by I. A. Murav′ev; E. A. Kechatov; Yu. I. Smetanin
- Book ID
- 112489408
- Publisher
- Springer
- Year
- 1970
- Tongue
- English
- Weight
- 253 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0091-150X
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Three micronization techniques, based on the use of supercritical carbon dioxide, were investigated to produce microspheres of a natural biocompatible polysaccharide. Particles smaller than 20 µm were obtained by means of the rapid expansion of a supercritical solution method (RESS), both with and w
efficiency; the former gave the similar oil yield to that with tetralin solvent, while the latter did the lower yield because of its too high hydrogen acceptability. The liquefaction scheme for the higher efficiency is discussed in terms of reaction conditions including catalysts and solvents.