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Production of a human monoclonal antibody recognising a determinant on mouse IgG2b from a patient receiving mouse monoclonal antibody for diagnostic imaging

โœ Scribed by Lindy G. Durrant; R. Adrian Robins; Kenneth C. Ballantyne; Eric B. Austin; Robert W. Baldwin


Book ID
105309675
Publisher
Springer-Verlag
Year
1990
Tongue
English
Weight
660 KB
Volume
31
Category
Article
ISSN
0340-7004

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Rats were injected both intradermally and intravenously with an IgG2b mouse monoclonal antibody (791T/36) and subsequently the biodistribution of intravenously injected 111In labelled antibody was examined by gamma camera imaging in these and control rats. The majority of pretreated rats showed a ma