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Production of 3,4-dihydroxy phenyl-l-alanine (l-DOPA) by Egyptian halophilic black yeast

✍ Scribed by Doaa A. R. Mahmoud; Magda A. El Bendary

Publisher
Springer
Year
2010
Tongue
English
Weight
429 KB
Volume
27
Category
Article
ISSN
1573-0972

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Oxidation of 3-(3,4-dihydroxy phenyl)-l-
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✍ B. S. Sherigara; B. E. Kumara Swamy; E. V. S. Subrahmanyam; K. Ishwar Bhat πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 117 KB

## Abstract Manganese(III) (Mn(III)) has been stabilized in weakly acidic solution by means of pyrophosphate and the nature of the complex was elucidated spectrophotometrically. Stoichiometry of Mn(III)‐oxidation of levodopa and methyl dopa in pyrophosphate medium was established in the pH range 2.

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As an alternative approach to the production of L-DOPA from a cheap raw material, we constructed a hybrid pathway consisting of toluene dioxygenase, toluene cis-glycol dehydrogenase, and tyrosine phenol-lyase. In this pathway, catechol is formed from benzene through the sequential action of toluene