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Production of 1α,25-Dihydroxy-3-epi-vitamin D3 in two rat osteosarcoma cell lines (UMR 106 and ROS 17/2.8): existence of the C-3 epimerization pathway in ROS 17/2.8 cells in which the C-24 oxidation pathway is not expressed

✍ Scribed by M.-L Siu-Caldera; H Sekimoto; A Weiskopf; P Vouros; K.R Muralidharan; W.H Okamura; J Bishop; A.W Norman; M.R Uskoković; I Schuster; G.S Reddy


Book ID
117808805
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
102 KB
Volume
24
Category
Article
ISSN
8756-3282

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## Abstract In a recent study, we investigated the metabolism of 1α,25‐dihydroxy‐20‐epi‐vitamin D~3~ (1α,25(OH)~2~‐20‐epi‐D~3~), a potent synthetic vitamin D~3~ analog in the isolated perfused rat kidney and proposed that the enhanced biological activity of 1α,25(OH)~2~‐20‐epi‐D~3~ is in part due t