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Production of 1,25-Dihydroxyvitamin D3 by Pulmonary Alveolar Macrophages from Patients with Sarcoidosis

โœ Scribed by JOHN S. ADAMS; MERCEDES A. GACAD; FREDERICK R. SINGER; OM P. SHARMA


Book ID
118723297
Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
426 KB
Volume
465
Category
Article
ISSN
0890-6564

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We have reported that the active form of vitamin D3, 1 alpha,25-dihydroxyvitamin D3 [1 alpha,25(OH)2D3], directly induces activation and fusion of mouse alveolar macrophages (Abe et al., 1983, 1984). The activated state appeared to be a prerequisite to the fusion of macrophages. Macrophages began to