## Abstract The use of lentiviral vectors as gene delivery vehicles has become increasingly popular in recent years. The growing interest in these vectors has created a strong demand for large volumes of vector stocks, which entails the need for scaleable vector manufacturing procedures. In this wo
Production and purification of lentiviral vectors generated in 293T suspension cells with baculoviral vectors
β Scribed by Lesch, H P; Laitinen, A; Peixoto, C; Vicente, T; Makkonen, K-E; Laitinen, L; Pikkarainen, J T; Samaranayake, H; Alves, P M; Carrondo, M J T
- Book ID
- 109855411
- Publisher
- Nature Publishing Group
- Year
- 2011
- Tongue
- English
- Weight
- 526 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0969-7128
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## Abstract ## Background Gene delivery in dendritic cells (DC) has raised considerable interest to modulate DC functions and induce therapeutic immunity or tolerance in an antigenβspecific fashion. Among immature DC, Langerhans cells (LC) are attractive candidates for antigen delivery using lenti